American Ginseng > Interactions

Nutritional Supplement

American Ginseng

  • Negative Interactions

    1
    • American Ginseng

      Warfarin

      Potential Negative Interaction

      In a study of healthy human volunteers, supplementing with American ginseng reduced warfarin's anticoagulant effect, apparently by stimulating the body to accelerate the metabolism of warfarin. People taking warfarin should not take American ginseng, unless supervised by a doctor.

      Warfarin
      American Ginseng
      ×
      1. Yuan CS, Wei G, Dey L, et al. Brief communication: American ginseng reduces warfarin's effect in healthy patients: a randomized, controlled Trial. Ann Intern Med 2004;141:23-7.

References

1. Shibata S, Tanaka O, Shoji J, Saito H. Chemistry and pharmacology of Panax. Econ Med Plant Res 1:218–84.

2. Morris AC, Jacobs I, McLellan TM, et al. No ergogenic effect on ginseng ingestion. Int J Sport Nutr 1996;6:263-71.

3. Vuksan V, Sivenpiper JL, Koo VYY, et al. American ginseng (Panax quinquefolius L.) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000;160:1009-13.

4. Duke J. Ginseng: A Concise Handbook. Algonac, MI: Reference Publications, 1989, 36.

5. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine: Materia Medica. Seattle: Eastland Press, 1993, 358-9.

6. Foster S. Herbs for Health. Loveland, CO: Interweave Press, 1996, 48-9.

7. Yun TK, Choi Y. Preventive effect of ginseng intake against various human cancers: A case-control study on 1987 pairs. Cancer Epidem Biomarkers Prev 1995;4:401-8.