Copper > Sources & Forms

Nutritional Supplement

Copper

Where to Find It

The best source of copper is oysters. Nuts, dried legumes, cereals, potatoes, vegetables, and meat also contain copper.

How to Use It

Most people consume less than the recommended amount of this mineral. Some doctors recommend supplementing the average diet with 1–3 mg of copper per day. While the necessity of supplementing a normal diet with copper has not been proven, most people who take zinc supplements, including the zinc found in multivitamin-mineral supplements, should probably take additional copper.

Cupric oxide (CuO) is a form of copper frequently used in vitamin-mineral supplements sold over-the-counter. However, animal studies have shown conclusively this form of copper is poorly absorbed from the gut; it should therefore not be used in supplements.1,2,3,4 Several other forms of copper (including copper sulfate, cupric acetate, and alkaline copper carbonate) are better absorbed, and are therefore preferable to cupric oxide.5

References

1. Aoyogi S, Baker DH. Bioavailability of copper in analytical-grade and feed-grade inorganic copper sources when fed to provide copper at levels below the chicks requirement. Poult Sci 1993;72:1075-83.

2. Baker DH, Odle J, Funk MA, Wieland TM. Bioavailability of copper in cupric oxide, cuprous oxide and in a copper-lysine complex. Poult Sci 1991;70:177-9.

3. Cromwell GL, Stahly TS, Moneque HJ. Effects of source and level of copper on performance and liver copper stores in weanling pigs. J Anim Sci 1989;67:2996-3002.

4. Ledoux DR, Henry PR, Ammerman CB, et al. Estimation of the relative bioavailability of inorganic copper sources for chicks using tissue uptake of copper. J Anim Sci 1991;69:215-22.

5. Baker DH. Cupric oxide should not be used as a copper supplement for either animals or humans. J Nutr 1999;129:2278-9.

6. Sandstead HH. Requirements and toxicity of essential trace elements, illustrated by zinc and copper. Am J Clin Nutr 1995;61(suppl):621S-24S [review].

7. Broun ER. Greist A, Tricot G, Hoffman R. Excessive zinc ingestion. A reversible cause of sideroblastic anemia and bone marrow depression. JAMA 1990;264:1441-3.

8. Jacob RA, Skala JH, Omaye ST, Turnlund JR. Effect of varying ascorbic acid intakes on copper absorption and ceruloplasmin levels of young men. J Nutr 1987;117:2109-15.

9. Ford ES. Serum copper concentration and coronary heart disease among US adults. Am J Epidemiol 2000;151:1182-8.

10. Youssef A, Wood B, Baron DN. Serum copper: a marker of disease activity in rheumatoid arthritis. J Clin Pathol 1983;36:14-17.